Physical Education
Hossein TaheriChadorneshin; Mohammad Esmaiel Afzalpour; Ehsan Afroozi-Gerow; Seyed Hosein Abtahi-Eivary; Meysam Alipour-Raz
Volume 26, Issue 1 , March and April 2019, , Pages 99-107
Abstract
Reactive oxygen species (ROS) result in serious damage oxidation of proteins, lipids and genomic structures. Studies have shown that production of ROS increases during intensive exercise training. The aim of present study was to investigate the effect of two type sprint and endurance exercise trainings ...
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Reactive oxygen species (ROS) result in serious damage oxidation of proteins, lipids and genomic structures. Studies have shown that production of ROS increases during intensive exercise training. The aim of present study was to investigate the effect of two type sprint and endurance exercise trainings on 8-oxoguanine DNA glycosylase (OGG1) and hydroxy-2'-deoxyguanosine (8-OHdG) levels in the brain and liver of Wistar rats. 24 adult Albino Wistar rats were randomly divided into sedentary control, sprint exercise training, and endurance exercise training groups. Rats in sprint and endurance exercise training groups ran on treadmill for 6 weeks, 6 days per week, at 80 to 100 percent of maximal oxygen consumption. OGG1 and 8-OHdG levels were measured using sandwich ELISA assay. Data analyzed using one way ANOVA at P≤0.05 level. Results showed that both of sprint and endurance exercise trainings result in significant increase in OGG1 levels in brain and liver. Sprint exercise training resulted in greater increase in brain OGG1 than endurance exercise training. However, sprint and endurance exercise training had no significant effect on 8-OHdG levels in brain and liver tissues. OGG1 content correlated negatively with 8-OHdG levels. Collectively, sprint and endurance exercise trainings prevents from genomic structure through an increase in OGG1 contents.
Physical Education
Hossein TaheriChadorneshin; mysam alipour raz; Mohammad Reza Yousefi; Sakineh Mokhtari-Motameni-Shivan
Volume 25, Issue 3 , July and August 2018, , Pages 441-450
Abstract
Background: Bruce and Cooper tests are used to determine the maximum oxygen consumption. However, the response of the indicators of muscle cell damage (Lactate dehydrogenase, Creatine kinase), cardiac (Creatine kinase-MB), and liver (Aspartate aminotransferase, Alanine aminotransferase and Alkaline phosphatase) ...
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Background: Bruce and Cooper tests are used to determine the maximum oxygen consumption. However, the response of the indicators of muscle cell damage (Lactate dehydrogenase, Creatine kinase), cardiac (Creatine kinase-MB), and liver (Aspartate aminotransferase, Alanine aminotransferase and Alkaline phosphatase) have not been compared following Bruce and Cooper tests.Materials and Methods: For this purpose, 18 sedentary male students (age: 20.88 ± 2.27 years, body mass index 22.67 ± 1.36 kg/m2), performed Bruce and Cooper protocols in two separate periods (one month interval). Blood sampling was taken before, immediately, 24 and 48 hours after each test. Serum concentrations of dependent variables were determined by commercial kits. Repeated measure and covariance analysis has been used to evaluated statistical difference in inter and intra group at P